Surgical Informed Consent has long been recognized as an important component of modern medicine. The ultimate goals of SIC are to improve clients’ understanding of the intended procedure, increase client satisfaction, maintain trust between clients and health providers, and ultimately minimize litigation issues related to surgical procedures. The purpose of the current study is to assess the comprehensiveness of the SIC process for women undergoing obstetric and gynecologic surgeries. A hospital-based cross-sectional study was undertaken at Hawassa University Comprehensive Specialized Hospital (...) in November and December, 2016. A total of 230 women who underwent obstetric and/or gynecologic surgeries were interviewed immediately after their hospital discharge to assess their experience of the SIC process. Thirteen components of SIC were used based on international recommendations, including the Royal College of Surgeon’s standards of informed consent practices for surgical procedures. Descriptive summaries are presented in tables and figures. Forty percent of respondents were aged between 25 and 29 years. Nearly a quarter had no formal education. More than half of respondents had undergone an emergency surgical procedure. Only 18.4% of respondents reported that the surgeon performing the operation had offered SIC, while 36.6% of respondents could not recall who had offered SIC. All except one respondent provided written consent to undergo a surgical procedure. However, 8.3% of respondents received SIC service while already on the operation table for their procedure. Only 73.9% of respondents were informed about the availability of alternative treatment options. Additionally, a majority of respondents were not informed about the type of anesthesia to be used and related complications. Only 54.2% of respondents reported that they had been offered at least six of the 13 SIC components used by the investigators. There is gap in the provision of comprehensive and standardized pre-operative counseling for obstetric and gynecologic surgeries in the study hospital. This has a detrimental effect on the overall quality of care clients receive, specifically in terms of client expectations and information needs. (shrink)

In this paper I argue that meditation has a direct bearing upon philosophical discourse by enabling us to distance ourselves from the basic structure of subjectivity that often limits the scope of reason. Recent neurobiological hypotheses are discussed in conjunction with the method of hermeneutic phenomenology to argue that interpretations on the level of our neurobiology underly and construct our experience of ourselves as subjects and the sense of explicit rational understanding that arises from it. This implies that prediscursive embodied (...) practice can play a crucial role in freeing our philosophical understanding from implicit assumptions. (shrink)

This paper examines the role of managerial self-interest in the merger market. It looks at factors influencing managers'' merger decisions by analyzing managerial expense preference factors on cross-sectional data employing non-parametric statistical methods. The same factors are examined for acquiring, acquired, and merging firms, and control groups used in each case. The results support the authors'' contention that managerial discretion is a significant motivating factor for mergers. The changes in expense preference factors indicate management decisions which provide conditions allowing management (...) to indulge in management preferred expenditures, while reducing risk to their career. The authors then provide a moral/philosophic framework of ethical analysis for examining manager''s merger decisions, using teleological and deontological theories. They conclude that merger decisions motivated or influenced by self-interest are unethical and, in the process, provide managers facing a merger decision with a framework for making an ethical decision. (shrink)

Replication protein A (RPA), the major single‐stranded DNA‐binding protein in eukaryotic cells, is required for processing of single‐stranded DNA (ssDNA) intermediates found in replication, repair, and recombination. Recent studies have shown that RPA binding to ssDNA is highly dynamic and that more than high‐affinity binding is needed for function. Analysis of DNA binding mutants identified forms of RPA with reduced affinity for ssDNA that are fully active, and other mutants with higher affinity that are inactive. Single molecule studies showed that (...) while RPA binds ssDNA with high affinity, the RPA complex can rapidly diffuse along ssDNA and be displaced by other proteins that act on ssDNA. Finally, dynamic DNA binding allows RPA to prevent error‐prone repair of double‐stranded breaks and promote error‐free repair. Together, these findings suggest a new paradigm where RPA acts as a first responder at sites with ssDNA, thereby actively coordinating DNA repair and DNA synthesis. (shrink)

This book presents a multidisciplinary perspective on chance, with contributions from distinguished researchers in the areas of biology, cognitive neuroscience, economics, genetics, general history, law, linguistics, logic, mathematical physics, statistics, theology and philosophy. The individual chapters are bound together by a general introduction followed by an opening chapter that surveys 2500 years of linguistic, philosophical, and scientific reflections on chance, coincidence, fortune, randomness, luck and related concepts. A main conclusion that can be drawn is that, even after all this time, (...) we still cannot be sure whether chance is a truly fundamental and irreducible phenomenon, in that certain events are simply uncaused and could have been otherwise, or whether it is always simply a reflection of our ignorance. Other challenges that emerge from this book include a better understanding of the contextuality and perspectival character of chance (including its scale-dependence), and the curious fact that, throughout history (including contemporary science), chance has been used both as an explanation and as a hallmark of the absence of explanation. As such, this book challenges the reader to think about chance in a new way and to come to grips with this endlessly fascinating phenomenon. (shrink)

Im Zentrum des vorliegenden Sammelbandes steht die Frage nach dem Bösen in Religionen, die als monotheistisch verstanden werden oder für die zumindest die Herrschaft des Hauptgottes über alle anderen Götter und Mächte ein entscheidendes Anliegen ist. Der Schwerpunkt liegt auf dem sich formierenden Judentum und Christentum sowie dem Alten Testament. Besonderes Interesse gilt den Texten aus Qumran, und darüber hinaus erfolgt ein Blick auf mittelalterliche Heiligenlegenden. Die Beiträge des Bandes zeigen, dass es in den antiken jüdischen und christlichen Texte eine (...) große Vielfalt von Verkörperungen des Bösen gibt, sei es extern als Dämon oder Teufel, sei es intern als die menschliche Fähigkeit, Böses zu tun. Außerdem stellt sich heraus, dass in der jüdisch-christlichen Literatur Dualismus nicht grundsätzlich abgelehnt wird, aber nur Formen von Dualismus vorkommen, in denen das Böse Gott und dem Guten letztlich untergeordnet ist. Mit Beiträgen von: Jörn Bockmann, Miryam T. Brand, Jan Dochhorn, Matthew Goff, Erkki Koskenniemi, Michael Morris, Hector M. Patmore, Susanne Rudnig-Zelt, Markus Saur, Ryan E. Stokes, Oda Wischmeyer, Benjamin Wold. (shrink)

Fifteen Million Merits depicts a reality remarkably similar to our own, in which technology has developed to the point where we could, in principle, work less, and reproduce the basic goods and services needed to survive into the future without arduous effort. Nevertheless, we cycle endlessly, towards nothing, and the only motivation keeping our feet rigidly attached to our peddles is vacuous entertainment in the form of pornography, video games, cruel comedy, and the improbable prospect of becoming a celebrity. (...) Each of these lurid topics is explored in this chapter, with a special focus on the philosophers Marx, Marcuse, Adorno, and Lukacs. Finally, the issue as to whether or not resisting entertainment‐capitalist is possible is raised and addressed, albeit with pessimism. (shrink)

This essay revisits some classic problems in the philosophy of space and time concerning the counting of possibilities. I argue that we should think that two Newtonian worlds can differ only as to when or where things happen and that general relativistic worlds can differ in something like the same way—the first of these theses being quaintly heterodox, the second baldly heretical, according to the mores of contemporary philosophy of physics.

The most recent work toward compiling a comprehensive database of adenosine‐to‐inosine RNA editing events suggests that the potential for RNA editing is much more pervasive than previously thought; indeed, it is manifest in more than 100 million potential editing events located primarily within Alu repeat elements of the human transcriptome. Pairs of inverted Alu repeats are found in a substantial number of human genes, and when transcribed, they form long double‐stranded RNA structures that serve as optimal substrates for RNA (...) editing enzymes. A small subset of edited Alu elements has been shown to exhibit diverse functional roles in the regulation of alternative splicing, miRNA repression, and cis‐regulation of distant RNA editing sites. The low level of editing for the remaining majority may be non‐functional, yet their persistence in the primate genome provides enhanced genomic flexibility that may be required for adaptive evolution. (shrink)

Models of collective deliberation often assume that the chief aim of a deliberative exchange is the sharing of information. In this paper, we argue that an equally important role of deliberation is to draw participants’ attention to pertinent questions, which can aid the assembly and processing of distributed information by drawing deliberators’ attention to new issues. The assumption of logical omniscience renders classical models of agents’ informational states unsuitable for modelling this role of deliberation. Building on recent insights from psychology, (...) linguistics and philosophy about the role of questions in speech and thought, we propose a different model in which beliefs are treated as answers directed at specific questions. Here, questions are formally represented as partitions of the space of possibilities and individuals’ information states as sets of questions and corresponding partial answers to them. The state of conversation is then characterised by individuals’ information together with the questions under discussion, which can be steered by various deliberative inputs. Using this model, deliberation is then shown to shape collective decisions in ways that classical models cannot capture, allowing for novel explanations of how group consensus is achieved. (shrink)

This paper analyses the Marxian theory of exploitation. The axiomatic approach standard in social choice theory is adopted in order to study the concept of exploitation—what it is and how it should be captured empirically. Two properties are presented that capture some fundamental Marxian insights. It is shown that, contrary to the received view, there exists a nonempty class of definitions of exploitation that preserve the relation between exploitation and profits—called Profit-Exploitation Correspondence Principle—in general economies with heterogeneous agents, complex class (...) structures, and production technologies with heterogeneous labour inputs. However, among the main approaches, only the so-called ‘New Interpretation’ satisfies the Profit-Exploitation Correspondence Principle in general. (shrink)

For over two decades, the debate about whether legally to recognize environmental refugees as refugees has been ongoing. Because their numbers are growing, environmental refugees should be recognized as convention refugees or a new UN convention should be drafted to address their needs. A typology of the environmental refugee should be developed to make the term more concrete and useful.

Is morality as we share it a good place to start on a large question of responsibility?

L'histoire n'est pas avare de paradoxe. C'est à Alger qu'est signée l'ordonnance du 21 avril 1944 qui accorde aux femmes françaises le droit de vote, mais c'est aussi à Alger, ou plus exactement en Algérie, que son champ d'application fut le plus restreint : si les Algériennes de souche européenne ont bénéficié des dispositions nouvelles, les Algériennes musulmanes, soit environ un million et demi de femmes, ont été privées du droit de vote. Si l'ordonnance du 7 mars 1944 qui (...) proclam... (shrink)

L'histoire n'est pas avare de paradoxe. C'est à Alger qu'est signée l'ordonnance du 21 avril 1944 qui accorde aux femmes françaises le droit de vote, mais c'est aussi à Alger, ou plus exactement en Algérie, que son champ d'application fut le plus restreint : si les Algériennes de souche européenne ont bénéficié des dispositions nouvelles, les Algériennes musulmanes, soit environ un million et demi de femmes, ont été privées du droit de vote. Si l'ordonnance du 7 mars 1944 qui (...) proclam... (shrink)

Popular science writing is, for the most part, undertaken by two different, if sometimes intersecting, classes of author: the intelligent general writer, often a journalist who has a deep interest in a particular scientific subject; and the versatile scientist who can place easy hands on a keyboard. Some writers in the former group, such as Richard Rhodes, interweave personality and topic to produce a compelling narrative. Others, such as Roger Lewin, write so clearly and vividly that the essential features of (...) their subject stand out in bold relief, giving readers entrée to an often-forbidding scientific domain. Scientists who attempt the genre may display those same virtues, and the very best write with an authority that commands the attention not only of a literate public but of their colleagues as well. In their popular writing, these latter can even shift scientific discourse and bring forward new theories, or at least new perspectives. (shrink)

People and the events that can lead to war in history, with ideas on philosophy, psychology, and culture.

A guide for making the future go better. Humanity’s written history spans only five thousand years. Our yet-unwritten future could last for millions more – or it could end tomorrow. Staggering numbers of people will lead lives of flourishing or misery or never live at all, depending on what we do today.

Navigation ability varies widely across humans. Prior studies have reported that being younger and a male has an advantage for navigation ability. However, these studies have generally involved small numbers of participants from a handful of western countries. Here, we review findings from our project Sea Hero Quest, which used a video game for mobile and tablet devices to test 3.9 million people on their navigation ability, sampling across every nation-state and from 18 to 99 years of age. Results (...) revealed that the task has good ecological validity and across all countries sufficiently sampled (N = 63), age is linked to a near-linear decline in navigation ability from the early 20s. All countries showed a male advantage, but this varied considerably and could be partly predicted by gender inequality. We found that those who reported growing up in a city were on average worse at navigating than those who grew up outside cities and that navigation performance helped identify those at greater genetic risk of Alzheimer's disease. We discuss the advantages and challenges of using a mobile app to study cognition and the future avenues for understanding individual differences in navigation ability arising from this research. (shrink)

Navigation ability varies widely across humans. Prior studies have reported that being younger and a male has an advantage for navigation ability. However, these studies have generally involved small numbers of participants from a handful of western countries. Here, we review findings from our project Sea Hero Quest, which used a video game for mobile and tablet devices to test 3.9 million people on their navigation ability, sampling across every nation-state and from 18 to 99 years of age. Results (...) revealed that the task has good ecological validity and across all countries sufficiently sampled (N = 63), age is linked to a near-linear decline in navigation ability from the early 20s. All countries showed a male advantage, but this varied considerably and could be partly predicted by gender inequality. We found that those who reported growing up in a city were on average worse at navigating than those who grew up outside cities and that navigation performance helped identify those at greater genetic risk of Alzheimer's disease. We discuss the advantages and challenges of using a mobile app to study cognition and the future avenues for understanding individual differences in navigation ability arising from this research. (shrink)